It doesn't incorporate all details about the feasible uses, directions, warnings, precautions, interactions, adverse consequences, or risks that may apply to modafinil. This information and facts is not precise professional medical assistance and does not switch facts you get through the healthcare provider. You must speak with the Health care provider for comprehensive specifics of the challenges and advantages of applying this drugs.
modafinil will boost the stage or effect of rabeprazole by affecting hepatic enzyme CYP2C19 metabolism. Minor/Significance Mysterious. Web effect on pantoprazole steps unidentified because of opposing consequences of CYP450 enzymes; watch
C: Use with warning if Rewards outweigh threats. Animal studies exhibit possibility and human experiments not offered or neither animal nor human research finished.
This facts really should not be made use of to choose if to get modafinil or every other medicine. Just the Health care service provider has the understanding and teaching to pick which medicines are suitable for a certain client. This details won't endorse any medication as Secure, productive, or accepted for managing any patient or wellness affliction. This really is only a short summary of normal details about this medication.
Keep track of click here Closely (1)mitotane decreases amounts of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Mitotane is a robust inducer of cytochrome P-4503A4; observe when coadministered with CYP3A4 substrates for feasible dosage changes.
Indicated to enhance wakefulness in Grown ups with excessive sleepiness connected to change operate disorder (SWD)
In keeping with some preliminary scientific tests, modafinil could act by partially inhibiting the dopamine transporter
Modafinil will not likely overcome obstructive snooze apnea or address its underlying brings about. Comply with your health practitioner's Guidance about your other remedies for this disorder.
These agreements had been subject to authorized scrutiny and antitrust investigations, culminating within a ruling via the Courtroom of Appeals in 2016, which uncovered the settlements didn't violate antitrust laws.[227]
These are generally not every one of the Negative effects which will arise. For those who have questions on Unwanted side effects, get in touch with your health care provider. Connect with your doctor for medical tips about Negative effects.
rifabutin will decrease the level or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Warfarin's less strong R-enantiomer is metabolized partly by CYP3A4 (and in addition CYP1A2 and CYP2C19). Watch INR additional commonly if coadministered with inhibitors of those isoenzymes and change warfarin dose if necessary.
acetazolamide will improve the degree or result of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
stiripentol will raise the stage or outcome of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Intently. Look at reducing the dose of CYP2C19 substrates, if adverse reactions are professional when administered concomitantly with stiripentol.